Brief overview of Polycystic ovary syndrome (PCOS)
PCOS is the most common endocrinopathy in women of reproductive age, and a leading cause of infertility, which makes its identification essential. The goals of treatment are to reduce hyperandrogenism and to induce fertility.
Common complaints
amenorrhea or oligomenorrhea
Weight gain
Fine hair growth on her face
Velvety thickening of the skin on the neck.
Differential diagnoses
Thyroid dysfunction
Cushing syndrome
Androgen-secreting neoplasms
Laboratory tests
Pregnancy test, urine (HCG)
Follow up with
serum total and free testosterone
serum dehydroepiandrosterone sulfate (DHEAS)
serum 17-hydroxyprogesterone
serum prolactin
serum thyroid-stimulating hormone
fasting lipid panel
pelvic ultrasound
Recommend treatment
weight loss
Start oral contraceptives
adjunct metformin
Reference
Goodarzi, M. (2019). Polycystic ovary syndrome. Epocrates. Retrieved from https://online.epocrates.com/diseases/14111/Polycystic-ovary-syndrome/Key-Highlights
amenorrhea or oligomenorrhea
Weight gain
Fine hair growth on her face
Velvety thickening of the skin on the neck.
Differential diagnoses
Thyroid dysfunction
Cushing syndrome
Androgen-secreting neoplasms
Laboratory tests
Pregnancy test, urine (HCG)
Follow up with
serum total and free testosterone
serum dehydroepiandrosterone sulfate (DHEAS)
serum 17-hydroxyprogesterone
serum prolactin
serum thyroid-stimulating hormone
fasting lipid panel
pelvic ultrasound
Recommend treatment
weight loss
Start oral contraceptives
adjunct metformin
Reference
Goodarzi, M. (2019). Polycystic ovary syndrome. Epocrates. Retrieved from https://online.epocrates.com/diseases/14111/Polycystic-ovary-syndrome/Key-Highlights
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